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成人慢性主动脉瓣疾病的评估。

Assessment of chronic aortic valve disease in adults.

作者信息

Harries A D, Griffiths B E

出版信息

Postgrad Med J. 1982 Jan;58(675):1-5. doi: 10.1136/pgmj.58.675.1.

Abstract

Chronic aortic valve disease is often tolerated for a long period of time with little in the way of symptoms, but once symptoms develop, the downhill course is often rapid. Medical therapy may alleviate symptoms of congestive heart failure and angina, but does not alter the natural history of the disease. The recent advances of cardiac surgery have, however, considerably improved the prognosis of most patients. Some patients with aortic regurgitation, though, will develop progressive congestive heart failure despite aortic valve replacement. Others with severe aortic stenosis will die suddenly while awaiting surgery as will a small number who previously had been asymptomatic. The information that comes from cardiac catheterization as well as the non-invasive investigation of cardiological disease, greatly enhanced by the introduction of the echocardiogram, has provided the physician with a better understanding of the particular problems in question and, therefore, the potential to solve them. This article aims to review the means by which high-risk groups can be identified, in order that their outlook may be improved especially with respect to the timing of surgical intervention.

摘要

慢性主动脉瓣疾病通常在很长一段时间内症状轻微,但一旦出现症状,病情往往迅速恶化。药物治疗可能会缓解充血性心力衰竭和心绞痛的症状,但不会改变疾病的自然病程。然而,心脏外科手术的最新进展已显著改善了大多数患者的预后。不过,一些主动脉瓣反流患者即使进行了主动脉瓣置换,仍会发展为进行性充血性心力衰竭。其他严重主动脉瓣狭窄患者在等待手术时会突然死亡,少数之前无症状的患者也会如此。通过心脏导管检查以及引入超声心动图后得到极大增强的心脏病无创检查所获得的信息,使医生能更好地了解相关特定问题,从而有解决这些问题的可能性。本文旨在综述识别高危人群的方法,以便改善他们的预后,特别是在手术干预时机方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe91/2426220/48bb366af5e8/postmedj00205-0007-a.jpg

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