Phillips W C, Kattapuram S V, Doseretz D E, Raymond A K, Schiller A L, Murphy G, Wyshak G
Radiology. 1982 Jul;144(2):285-90. doi: 10.1148/radiology.144.2.7045976.
A retrospective review was made of the pretreatment radiographs of 20 patients with well-documented primary lymphoma of bone. Nine radiographic signs were defined, and the presence or absence of each was recorded for each patient. When the radiographic findings were compared with disease-free survival for each patient, it was found that patients who had a relapse had a higher mean number of positive radiographic signs than those who remained disease free (p less than 0.02). Also, those who relapsed early had more positive signs than those who relapsed late (p less than 0.05). Certain signs, i.e., pathologic fracture, layered periosteal new bone, broken periosteal new bone, cortical breakthrough, soft-tissue mass, and soft-tissue swelling, were more helpful than others for making a prognosis. These signs appear to be related to radiologic evidence of imminent or actual soft-tissue extension of the tumor.
对20例有充分记录的原发性骨淋巴瘤患者的治疗前X线片进行了回顾性研究。定义了9种X线征象，并记录了每位患者每种征象的有无。当将X线表现与每位患者的无病生存率进行比较时，发现复发患者的阳性X线征象平均数量高于未复发患者（p<0.02）。此外，早期复发患者的阳性征象比晚期复发患者更多（p<0.05）。某些征象，即病理性骨折、分层骨膜新生骨、骨膜新生骨中断、皮质突破、软组织肿块和软组织肿胀，对预后的判断比其他征象更有帮助。这些征象似乎与肿瘤即将发生或实际发生软组织扩展的放射学证据有关。
