Berg B
Tissue Antigens. 1981 Nov;18(5):306-15. doi: 10.1111/j.1399-0039.1981.tb01397.x.
The influence of HLA-A, B-matching on the results of 362 cadaver renal transplantations was analyzed. Of these, 34 of the patients had diabetes and 105 were 55 years old or more. The case material was divided into groups, based on the number of HLA-A, B incompatibilities. The occurrence of factors having a possible bearing on kidney graft survival was determined in each match group. It was found that several of these factors, such as the immunosuppressive agents given and the number of high-risk patients, were unequally distributed in the various groups. This may be related to changes in policy that have occurred since the transplant unit was moved to Huddinge Hospital in November 1973. In order to obtain homogeneous case material, the Huddinge series was analyzed separately. A significant difference in survival was found in both materials between transplants with 2 or less incompatibilities and those with more than 2 incompatibilities. A significant difference in patient survival between these two groups was found in the total case material.
分析了HLA - A、B配型对362例尸体肾移植结果的影响。其中，34例患者患有糖尿病，105例患者年龄在55岁及以上。根据HLA - A、B不相容的数量将病例材料分组。在每个配型组中确定可能影响肾移植存活的因素的发生率。发现其中一些因素，如所给予的免疫抑制剂和高危患者的数量，在不同组中分布不均。这可能与1973年11月移植单位迁至胡丁厄医院后政策的变化有关。为了获得同质的病例材料，对胡丁厄系列进行了单独分析。在两份材料中，不相容数为2个或更少的移植与不相容数超过2个的移植之间在存活方面存在显著差异。在全部病例材料中，这两组患者的存活情况也存在显著差异。
