Andersson G B, Lereim P, Galante J O, Rostoker W
Acta Orthop Scand. 1982 Jun;53(3):349-54. doi: 10.3109/17453678208992227.
A study was made of bone ingrowth into fiber metal composite prostheses used to replace large segments of the femur in baboons. Bone grafts of two different types were used to cover the segment: chips of bone with large particle size and ground bone with a smaller particle size. The prosthetic segment was bridged by bone at 3 and 6 months in all cases irrespective of the structure of the transplant. In animals sacrificed at 6 months bone ingrowth occurred, with a marked difference between specimens with the two different grafts. In the ground bone specimens ingrowth occurred over the total surface area, and bone penetrated deep into the composite. With the chip grafts ingrowth was more irregular occurring only in some areas and it was always superficial. The difference is believed to be due to the improved contact between the fiber metal surface and the transplant. The lesser bulk of the ground transplant is advantageous when the soft tissue cover of the bone is thin.
对用于替换狒狒股骨大段的纤维金属复合假体的骨长入情况进行了一项研究。使用两种不同类型的骨移植来覆盖该段：大粒径的骨碎片和较小粒径的磨碎骨。无论移植结构如何，在所有情况下，假体段在3个月和6个月时均被骨桥接。在6个月处死的动物中出现了骨长入，两种不同移植的标本之间存在明显差异。在磨碎骨标本中，骨长入发生在整个表面积上，并且骨深入复合材料内部。对于碎骨移植，骨长入更不规则，仅在某些区域发生，并且总是浅表的。据信这种差异是由于纤维金属表面与移植物之间更好的接触所致。当骨的软组织覆盖层较薄时，磨碎移植物较小的体积是有利的。
