网织红细胞与胰岛素和红细胞的结合。
Reticulocytes and insulin binding to erythrocytes.
作者信息
Ivarsson S A, Thorell J I
出版信息
Acta Med Scand Suppl. 1981;656:23-7. doi: 10.1111/j.0954-6820.1982.tb07696.x.
The relationship between erythrocyte insulin receptors and the reticulocytes were studied in a group with a varying degree of reticulocytosis. The maximal I-insulin binding to erythrocytes varied between 6% and 37% and it showed a highly significant positive correlation with the reticulocyte count (r=0.85). The highest binding was found in a patient with hereditary spherocytosis and very active hematopoiesis (312 x 10(9) reticulocytes per litre). The results suggest that insulin receptors are predominantly localized to the young erythrocytes, and that further studies are needed to characterize the dependence of the receptor on erythrocyte maturation.
在一组存在不同程度网织红细胞增多的人群中，研究了红细胞胰岛素受体与网织红细胞之间的关系。红细胞对胰岛素的最大结合量在6%至37%之间变化，且与网织红细胞计数呈高度显著正相关（r = 0.85）。在一名患有遗传性球形红细胞增多症且造血非常活跃（每升有312×10⁹个网织红细胞）的患者中发现了最高结合量。结果表明，胰岛素受体主要定位于年轻红细胞，并且需要进一步研究来确定该受体对红细胞成熟的依赖性。
Zotero 插件