Fenoglio C M, Hayata T, Crum C P, Richart R M
Diagn Gynecol Obstet. 1982 Summer;4(2):97-103.
Four hundred eighty-eight lesions from 456 patients were surveyed for the production of hCG using the immunoperoxidase technique. HCG immunoreactivity was found in 9.1% of the total number of cases studied. The 10% of ovarian cancers expressing hCG included serous, endometrioid, and germ cell tumors. Eighteen point nine percent of neoplastic cervices were positive for hCG; the highest rate of expression was in invasive cancers. Eighteen point nine percent of endometrial cancers were hCG positive; poorly differentiated tumors had the highest percent of marker expression. The significance of "ectopic" hCG expression in nontrophoblastic gynecologic neoplasms is discussed.
采用免疫过氧化物酶技术对456例患者的488个病灶进行了人绒毛膜促性腺激素（hCG）产生情况的检测。在所研究的病例总数中，发现9.1%存在hCG免疫反应性。表达hCG的卵巢癌中有10%包括浆液性、子宫内膜样和生殖细胞肿瘤。18.9%的肿瘤性宫颈组织hCG呈阳性；表达率最高的是浸润性癌。18.9%的子宫内膜癌hCG呈阳性；低分化肿瘤的标志物表达率最高。文中讨论了非滋养细胞性妇科肿瘤中“异位”hCG表达的意义。
