Taylor P M
Lepr India. 1982 Jan;54(1):117-22.
For the early recognition of dapsone resistance, it is essential to regularly examine patients at risk for suspicious new lesions, backed by regular clinical treatment records including smear results. The earlier the recognition and starting on alternative treatment, the better is the response. However, it is not advisable to change treatment without attempting at least clinical confirmation, and endorsing the chart so that the problem is not missed on subsequent occasions.
为了早期识别氨苯砜耐药情况,必须定期检查有出现可疑新病灶风险的患者,并以包括涂片结果在内的常规临床治疗记录为依据。识别越早并开始采用替代治疗,反应就越好。然而,在未至少尝试进行临床确认并在病历上注明的情况下就改变治疗方案是不可取的,这样后续就不会遗漏该问题。