氯法齐明和氨苯砜联合耐药性麻风病。病例报告。
Combined clofazimine- and dapsone-resistant leprosy. A case report.
作者信息
Kar H K, Bhatia V N, Harikrishnan S
出版信息
Int J Lepr Other Mycobact Dis. 1986 Sep;54(3):389-91.
PMID:3528345
Abstract
A preliminary report is presented on the finding in a patient with lepromatous leprosy relapsing after maintaining clinical inactivity and bacterial negativity with dapsone monotherapy for a period of 23 years. Interestingly, Mycobacterium leprae from the fresh skin lesions revealed resistance to both clofazimine and dapsone by standard mouse foot pad testing.
摘要
本文报道了1例瘤型麻风患者的研究结果。该患者在接受氨苯砜单药治疗23年，病情保持临床静止且细菌学阴性后复发。有趣的是，通过标准的小鼠足垫试验，从该患者新鲜皮肤损害中分离出的麻风分枝杆菌对氯法齐明和氨苯砜均耐药。
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