Leclerc P, Capron F, de Fenoyl O, Bientz M, Rochemaure J
Poumon Coeur. 1982 Mar-Apr;38(2):101-10.
Advances in the therapy of tumors or for the maintenance of grafts have improved survival in a large number of patients, but at the price of repeated complications due to the induced immunodeficiency state. Pulmonary infections are a frequent occurrence, and while some are easily recognized and treated, others must be precisely diagnosed, as only early specific treatment can avoid the often fatal outcome. Various techniques have therefore been developed to obtain specimens for microorganism isolation before having ultimate recourse to a surgical lung biopsy. It is in this field that the most marked progress is currently being made. The different microorganisms responsible for these affections are reviewed, the majority being common to the immunodeficiency state, while others are encountered more frequently as a function of the underlying disorder and of the ecological conditions in each centre.
肿瘤治疗或移植物维持方面的进展提高了大量患者的生存率,但代价是因诱导免疫缺陷状态而反复出现并发症。肺部感染很常见,虽然有些感染易于识别和治疗,但其他感染必须精确诊断,因为只有早期特异性治疗才能避免往往致命的后果。因此,人们开发了各种技术,以便在最终求助于外科肺活检之前获取用于微生物分离的标本。目前正是在这一领域取得了最显著的进展。本文综述了导致这些感染的不同微生物,大多数微生物常见于免疫缺陷状态,而其他微生物则根据潜在疾病和每个中心的生态条件更频繁地出现。