阿昔洛韦与阿糖腺苷治疗疱疹性角膜溃疡的双盲临床试验。
Double-blind clinical trial of acyclovir and adenine arabinoside in herpetic corneal ulceration.
作者信息
Young B, Patterson A, Ravenscroft T
出版信息
Am J Med. 1982 Jul 20;73(1A):311-2. doi: 10.1016/0002-9343(82)90113-9.
PMID:7048918
Abstract
The results of a double-blind clinical trials of acyclovir and adenosine arabinoside (ara-A) in 93 patients with herpetic keratitis demonstrated a significantly faster healing rate for acyclovir (p less than 0.01). Ulcers in 45 (94 percent) of acyclovir-treated patients and 37 (82 percent) of ara-A-treated patients healed within 14 days. No serious side effects were observed.
摘要
对93例疱疹性角膜炎患者进行的阿昔洛韦和阿糖腺苷（ara - A）双盲临床试验结果表明，阿昔洛韦的愈合速度明显更快（p小于0.01）。在接受阿昔洛韦治疗的45例患者（94%）和接受阿糖腺苷治疗的37例患者（82%）中，溃疡在14天内愈合。未观察到严重副作用。
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