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阿昔洛韦与阿糖腺苷联合稀释倍他米松治疗盘状疱疹性角膜炎的疗效与毒性比较:一项双盲试验的初步结果

Comparison of the efficacy and toxicity of acyclovir and of adenine arabinoside when combined with dilute betamethasone in herpetic disciform keratitis: preliminary results of a double-blind trial.

作者信息

Collum L M, O'Connor M, Logan P

出版信息

Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 6):597-9.

PMID:6385356
Abstract

Acyclovir is an effective and relatively non-toxic antiviral agent which has recently been introduced for the treatment of herpes virus infections in man. When combined with dilute steroid, acyclovir heals herpetic disciform keratitis and preliminary results of a double-blind clinical trial suggest that it may be more effective and less toxic than adenine arabinoside in the treatment of this condition.

摘要

阿昔洛韦是一种有效且相对无毒的抗病毒药物,最近已被用于治疗人类疱疹病毒感染。当与稀释的类固醇联合使用时,阿昔洛韦可治愈疱疹性盘状角膜炎,一项双盲临床试验的初步结果表明,在治疗这种疾病方面,它可能比阿糖腺苷更有效且毒性更小。

相似文献

1
Comparison of the efficacy and toxicity of acyclovir and of adenine arabinoside when combined with dilute betamethasone in herpetic disciform keratitis: preliminary results of a double-blind trial.阿昔洛韦与阿糖腺苷联合稀释倍他米松治疗盘状疱疹性角膜炎的疗效与毒性比较:一项双盲试验的初步结果
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 6):597-9.
2
A double-blind comparative trial of acyclovir and adenine arabinoside in combination with dilute betamethasone in the management of herpetic disciform keratitis.阿昔洛韦与阿糖腺苷联合稀释倍他米松治疗盘状疱疹性角膜炎的双盲对照试验。
Curr Eye Res. 1987 Jan;6(1):221-4. doi: 10.3109/02713688709020094.
3
[Comparison of the effectiveness of acyclovir and vidarabine in superficial herpes keratitis].[阿昔洛韦与阿糖腺苷治疗浅层疱疹性角膜炎的疗效比较]
Klin Monbl Augenheilkd. 1987 Jul;191(1):30-2.
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Acyclovir (Zovirax) in herpetic disciform keratitis.阿昔洛韦(无环鸟苷)治疗盘状疱疹性角膜炎。
Br J Ophthalmol. 1983 Feb;67(2):115-8. doi: 10.1136/bjo.67.2.115.
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Treatment of herpes simplex keratitis: comparison of acyclovir and vidarabine.单纯疱疹性角膜炎的治疗:阿昔洛韦与阿糖腺苷的比较。
Can J Ophthalmol. 1984 Apr;19(3):107-11.
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Randomised double-blind trial of acyclovir (Zovirax) and adenine arabinoside in herpes simplex amoeboid corneal ulceration.阿昔洛韦(无环鸟苷)与阿糖腺苷治疗单纯疱疹性阿米巴样角膜溃疡的随机双盲试验
Br J Ophthalmol. 1985 Nov;69(11):847-50. doi: 10.1136/bjo.69.11.847.
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[Double-blind treatment of ocular herpes simplex: Vira-A and acyclovir].单纯疱疹性眼病的双盲治疗:碘苷与阿昔洛韦
Bull Soc Ophtalmol Fr. 1983 Jan;83(1):25-9.
8
Double-blind clinical trial of acyclovir and adenine arabinoside in herpetic corneal ulceration.阿昔洛韦与阿糖腺苷治疗疱疹性角膜溃疡的双盲临床试验。
Am J Med. 1982 Jul 20;73(1A):311-2. doi: 10.1016/0002-9343(82)90113-9.
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Acyclovir in herpes keratitis.阿昔洛韦用于疱疹性角膜炎。
Am J Med. 1982 Jul 20;73(1A):290-3. doi: 10.1016/0002-9343(82)90108-5.
10
A randomised double-blind clinical trial of acyclovir (Zovirax) and adenine arabinoside in herpes simplex corneal ulceration.阿昔洛韦(无环鸟苷)与阿糖腺苷治疗单纯疱疹性角膜溃疡的随机双盲临床试验
Br J Ophthalmol. 1982 Jun;66(6):361-3. doi: 10.1136/bjo.66.6.361.