Souheaver G T, Ryan J J, DeWolfe A S
J Clin Psychol. 1982 Jul;38(3):490-6. doi: 10.1002/1097-4679(198207)38:3<490::aid-jclp2270380305>3.0.co;2-k.
Administered the Halstead-Reitan Battery (HRB) of neuropsychological tests to 24 patients with advanced renal failure, 24 patients with neurological disorders, and 24 patients with medical and/or non-psychotic psychiatric conditions in order to assess the effects of uremic encephalopathy on human neuropsychological functioning. The groups did not differ significantly in age, education, verbal intelligence, or level of affective disturbance. Results indicated that the uremic and neurological groups were equal in overall level of neuropsychological impairment and that both were significantly more impaired than the medical-psychiatric group. However, the uremic group showed a pattern of deficits that was qualitatively different from both the neurological and medical-psychiatric groups. Results were discussed with reference to selective cortical dysfunctions in uremia and contrasted with earlier studies that did not consider differential sparing of abilities in renal patients.
对24名晚期肾衰竭患者、24名神经疾病患者以及24名患有内科和/或非精神病性精神疾病的患者进行了哈尔斯特德-赖坦神经心理成套测验(HRB),以评估尿毒症性脑病对人类神经心理功能的影响。这些组在年龄、教育程度、言语智力或情感障碍水平上没有显著差异。结果表明,尿毒症组和神经疾病组在神经心理损害的总体水平上相当,且两者均比内科-精神疾病组受损更严重。然而,尿毒症组表现出的缺陷模式在性质上与神经疾病组和内科-精神疾病组均不同。结合尿毒症中的选择性皮质功能障碍对结果进行了讨论,并与早期未考虑肾病患者能力差异保留情况的研究进行了对比。