Burggren W W, Randall D J
Respir Physiol. 1978 Aug;34(2):171-83. doi: 10.1016/0034-5687(78)90026-9.
Gill ventilation, stroke volume and frequency, %O2 utilization and oxygen uptake, and dorsal aortic blood oxygen tension, content, pH and oxygen affinity have been determined during normoxia and during a range of hypoxic exposures in the sturgeon, Acipenser Transmontanus. In air-equilibrated water gill ventilation was 350 ml/kg/min, % utilization was 35--40%, and oxygen uptake at 15 degrees C was 55--60 ml O2/kg/h. Dorsal aortic blood PO2 was 90 mm Hg and blood O2 content at a normal pHa of 7.84 was 7.0 vol%. Vg fell considerably through a reduction in branchial stroke volume when PIO2 was reduced from 150 to 100 mm Hg. Although % utilization remained unchanged, VO2 was halved, clearly identifying Acipenser as an O2 conformer with a critical O2 tension just below air saturation. At a PIO2 of 60 mm Hg VO2 was only 15% of that at normoxic levels falling to only 5% at a PIO2 of 30 mm Hg. There was no hypoxic bradycardia. There was no repayment of an oxygen debt even after severe hypoxic exposure in Acipenser, and pHa remained unchanged under all experimental conditions, a response incompatible with lactate or succinate production. It is concluded that the sturgeon reduces total energy expenditure during hypoxic exposure, rather than switching from aerobic to anaerobic metabolism.
在常氧条件下以及一系列低氧暴露过程中，对高首鲟（Acipenser Transmontanus）的鳃通气、每搏输出量和频率、氧气利用率和摄氧量，以及背主动脉血氧张力、含量、pH值和氧亲和力进行了测定。在与空气平衡的水中，鳃通气量为350毫升/千克/分钟，利用率为35% - 40%，15摄氏度时的摄氧量为55 - 60毫升氧气/千克/小时。背主动脉血氧分压为90毫米汞柱，在正常动脉血pH值7.84时，血氧含量为7.0容积%。当吸入氧分压从150毫米汞柱降至100毫米汞柱时，鳃通气量因鳃每搏输出量的减少而大幅下降。尽管利用率保持不变，但摄氧量减半，这清楚地表明高首鲟是一种氧顺应者，其临界氧张力略低于空气饱和度。在吸入氧分压为60毫米汞柱时，摄氧量仅为常氧水平时的15%，在吸入氧分压为30毫米汞柱时降至仅5%。没有出现低氧性心动过缓。即使在高首鲟经历严重低氧暴露后，也没有氧债偿还现象，并且在所有实验条件下动脉血pH值保持不变，这种反应与乳酸或琥珀酸的产生不相符。结论是，高首鲟在低氧暴露期间会降低总能量消耗，而不是从有氧代谢切换到无氧代谢。
