Friede H, Johanson B
Scand J Plast Reconstr Surg. 1982;16(1):41-53. doi: 10.3109/02844318209006569.
A final evaluation of the effect of early bone grafting (EBG) on facial growth was carried out. The sample included 19 bilateral and 42 unilateral cleft lip and palate patients with an age range of 15-20 years, which meant on average 16 years after the EBG procedure. Roentgencephalometric data indicated maxillary retrognathia in both cleft categories and also deficient vertical descent of the maxilla, especially in the anterior part. In about 40% of the bilateral and 50% of the unilateral cleft patients, the mid-facial growth attenuation had reached such magnitude that surgical advancement of the maxilla was necessary. Analysis of plaster casts revealed that in every second cleft area the EBG operation had made it possible to achieve continuity in the dental arch without the need for prosthodontic replacement of teeth. Fusion of the suture between the (pre)maxilla and vomer was suggested as the reason for the typical mid-facial morphology seen in our patients with the most pronounced growth impairment.
对早期植骨术（EBG）对面部生长的影响进行了最终评估。样本包括19例双侧唇腭裂患者和42例单侧唇腭裂患者，年龄在15至20岁之间，这意味着平均在EBG手术后16年。X线头影测量数据表明，两类腭裂患者均存在上颌后缩，上颌垂直向下发育不足，尤其是前部。约40%的双侧腭裂患者和50%的单侧腭裂患者，面中部生长发育不足已达到需要进行上颌骨手术前移的程度。石膏模型分析显示，在每一个腭裂区域，EBG手术都使得牙弓能够实现连续，而无需进行义齿修复。（前）上颌骨与犁骨之间缝线融合被认为是我们研究中生长发育受损最明显的患者出现典型面中部形态的原因。
