[胰岛素刺激的ATP生成与胰岛素对大鼠骨骼肌富含质膜颗粒中肌酸积累的作用关系]
[Relationship of insulin-stimulated ATP formation to insulin action on creatine accumulation in plasma membrane-enriched particles of rat skeletal muscles].
作者信息
Karelin A A, Vtiurin B V
出版信息
Vopr Med Khim. 1982 Jul-Aug;28(4):118-23.
PMID:7051546
Abstract
ATP accumulated in the enriched with cytoplasmic membranes particles, isolated from rat skeletal muscles, after incubation of the particles in the medium containing insulin. After boiling in a water-bath of the particulate fraction supernatants, incubated in the presence of insulin, total content of creatine was increased in the particles and the content of 1-14C creatine in the medium was decreased.
摘要
从大鼠骨骼肌分离得到的富含细胞质膜的颗粒，在含有胰岛素的培养基中孵育后，ATP会在这些颗粒中积累。在胰岛素存在的情况下对颗粒部分的上清液进行水浴煮沸后，颗粒中肌酸的总含量增加，而培养基中1-14C肌酸的含量降低。
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