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黑暗饲养大鼠光照后不同脑区血清素受体的变化。

Changes in serotonin receptors in different brain regions after light exposure of dark-reared rats.

作者信息

Murphy S, Uzbekov M G, Rose S P

出版信息

Neurosci Lett. 1980 May 1;17(3):317-21. doi: 10.1016/0304-3940(80)90043-9.

DOI:10.1016/0304-3940(80)90043-9
PMID:7052477
Abstract

Male rats dark-reared from birth until 50 days of age and then exposed to light for 3 h show significant increases in specific [3H]serotonin (5-[3H]HT) binding to P2 membranes from visual and motor cortex and superior colliculus (25, 65 and 23% respectively) as compared with normal and dark-reared littermates. These increases are transient and return to normal levels after 7 days. The role of 5-HT as a transmitter in the visual system is discussed.

摘要

雄性大鼠从出生起在黑暗环境中饲养至50日龄,然后暴露于光照下3小时,与正常饲养和黑暗饲养的同窝仔鼠相比,其视觉和运动皮层以及上丘的P2膜上特异性[3H]血清素(5-[3H]HT)结合显著增加(分别增加25%、65%和23%)。这些增加是短暂的,7天后恢复到正常水平。本文讨论了5-羟色胺作为视觉系统中一种神经递质的作用。

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Changes in serotonin receptors in different brain regions after light exposure of dark-reared rats.黑暗饲养大鼠光照后不同脑区血清素受体的变化。
Neurosci Lett. 1980 May 1;17(3):317-21. doi: 10.1016/0304-3940(80)90043-9.
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[Serotonin binding activity of light and heavy synaptosomes from different animal brain structures following light deprivation].[光剥夺后不同动物脑结构的轻、重突触体的血清素结合活性]
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Effect of light deprivation on binding activity of serotonin with light and heavy synaptosomes from various brain formations.
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