黑暗饲养大鼠光照后不同脑区血清素受体的变化。
Changes in serotonin receptors in different brain regions after light exposure of dark-reared rats.
作者信息
Murphy S, Uzbekov M G, Rose S P
出版信息
Neurosci Lett. 1980 May 1;17(3):317-21. doi: 10.1016/0304-3940(80)90043-9.
PMID:7052477
Abstract
Male rats dark-reared from birth until 50 days of age and then exposed to light for 3 h show significant increases in specific [3H]serotonin (5-[3H]HT) binding to P2 membranes from visual and motor cortex and superior colliculus (25, 65 and 23% respectively) as compared with normal and dark-reared littermates. These increases are transient and return to normal levels after 7 days. The role of 5-HT as a transmitter in the visual system is discussed.
摘要
雄性大鼠从出生起在黑暗环境中饲养至50日龄，然后暴露于光照下3小时，与正常饲养和黑暗饲养的同窝仔鼠相比，其视觉和运动皮层以及上丘的P2膜上特异性[3H]血清素（5-[3H]HT）结合显著增加（分别增加25%、65%和23%）。这些增加是短暂的，7天后恢复到正常水平。本文讨论了5-羟色胺作为视觉系统中一种神经递质的作用。
相似文献
1
Changes in serotonin receptors in different brain regions after light exposure of dark-reared rats.黑暗饲养大鼠光照后不同脑区血清素受体的变化。
Neurosci Lett. 1980 May 1;17(3):317-21. doi: 10.1016/0304-3940(80)90043-9.
2
[Serotonin binding activity of light and heavy synaptosomes from different animal brain structures following light deprivation].[光剥夺后不同动物脑结构的轻、重突触体的血清素结合活性]
Biull Eksp Biol Med. 1977 Sep;84(9):299-301.
3
Effect of light deprivation on binding activity of serotonin with light and heavy synaptosomes from various brain formations.
Neurosci Behav Physiol. 1980 Jan-Feb;10(1):33-5. doi: 10.1007/BF01182233.
4
[Role of visual impulsation on the age-dependent receptor properties of synaptosomal membranes].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 Nov-Dec;26(6):1291-5.
5
[Role of neuronal and neuropile serotonin in the visual analyzer].
Biull Eksp Biol Med. 1981 Apr;91(4):389-90.
6
Comparison of serotonin 5-HT1 receptors and innervation in the visual cortex of normal and dark-reared cats.正常饲养和暗饲养猫视觉皮层中5-羟色胺5-HT1受体与神经支配的比较。
J Comp Neurol. 1991 Oct 8;312(2):223-30. doi: 10.1002/cne.903120205.
7
Benzodiazepine receptors in the visual structures of monocularly deprived rats. Effect of light and dark adaptation.
Brain Res. 1985 Mar 11;329(1-2):143-50. doi: 10.1016/0006-8993(85)90519-0.
8
Role of visual impulsation in the development of receptor properties of synaptosomal membranes with age.视觉冲动在突触体膜受体特性随年龄发展中的作用。
Neurosci Behav Physiol. 1977 Apr-Jun;8(2):117-20. doi: 10.1007/BF01186940.
9
Ontogenesis of serotonin 'receptors' in different regions of rat brain.大鼠脑不同区域中血清素“受体”的个体发生
Brain Res. 1979 May 18;168(1):195-9. doi: 10.1016/0006-8993(79)90139-2.
10
Effects of sensory deprivation upon the development of transmitter systems in the visual system [proceedings].感觉剥夺对视觉系统中递质系统发育的影响[会议论文集]
Act Nerv Super (Praha). 1977 May;19(2):154-6.
引用本文的文献
1
An autism-associated serotonin transporter variant disrupts multisensory processing.一种与自闭症相关的血清素转运体变体破坏多感官处理。
Transl Psychiatry. 2017 Mar 21;7(3):e1067. doi: 10.1038/tp.2017.17.
Zotero 插件