Hamilton R C, Broad A J, Sutherland S K
Neurosci Lett. 1980 Aug;19(1):45-50. doi: 10.1016/0304-3940(80)90253-0.
Isolated rat phrenic nerve diaphragm preparations were exposed to the venom of the Eastern brown snake (Pseudonaja textilis). The venom increased the number of 'coated omega figures' in the axolemma of the nerve terminals. The number of synaptic vesicles appeared to be decreased. The increase in coated omega figures in the axolemma is either caused by neurotoxins in the venom slowing down synaptic vesicle recycling or, after binding to axolemmal receptor, being internalized by receptor-mediated endocytosis. Synaptic vesicle recycling and receptor-mediated endocytosis may be related processes in motor nerve terminals.
将分离的大鼠膈神经膈肌标本暴露于东部棕蛇（伪眼镜蛇）的毒液中。毒液增加了神经末梢轴膜中“包被ω形结构”的数量。突触小泡的数量似乎减少了。轴膜中包被ω形结构的增加要么是由于毒液中的神经毒素减缓了突触小泡的循环，要么是在与轴膜受体结合后，通过受体介导的内吞作用被内化。突触小泡循环和受体介导的内吞作用可能是运动神经末梢中的相关过程。
