Petschen I, Minguell J, Amador R, Tormo A
Rev Esp Oncol. 1981;28(1):59-81.
The authors study 31 cases of Ewing's sarcoma. The survival after 5 years in only 25% for the initially localized tumors because lung and bone metastases finally develop in spite of any treatment. Polychemotherapy defers the appearance of metastases and increases the number of survivors. Patients being less than 15 years old offer a worst prognosis. The tumor localization, existence of general symptoms and their duration, and the alterations of the blood picture were not related with significant variations in the evolution of the Ewing's sarcoma in the studied cases. Probably the prophylactic irradiation of the lungs delays the appearance of metastases.
作者研究了31例尤因肉瘤。最初局限的肿瘤5年后生存率仅为25%,因为尽管进行了任何治疗,最终仍会发生肺和骨转移。多药化疗可延缓转移的出现并增加幸存者数量。年龄小于15岁的患者预后最差。在所研究的病例中,肿瘤的部位、全身症状的存在及其持续时间以及血象变化与尤因肉瘤的病程无显著差异。肺部预防性放疗可能会延缓转移的出现。