Le Mevel B, Mathe G, Jasmin C, Durand M, Brossel R, Chenal C, Guerin D, Kenesi C, Tomeno B, Mazabraud A, Sancho H
Nouv Presse Med. 1980 Feb 2;9(6):359-62.
The local treatment of Ewing's sarcoma by radiotherapy is classically linked to a very poor prognosis : 10 to 15% of 5 years survival, 75 to 95% of distant metastasis in 2 years. The combination of local radiotherapy to a systemic adjuvant chemotherapy have been recently shown to give a real benefit to this prognosis. The therapeutic trial of the EORTC and GETO, presented here allows us to hope a disease free survival at 5 years for 50% of our patients and a complete survival at 5 years for 56% of them.
5年生存率为10%至15%,2年内远处转移率为75%至95%。最近研究表明,局部放疗与全身辅助化疗相结合对改善这种预后有实际益处。本文介绍的欧洲癌症研究与治疗组织(EORTC)和德国骨肉瘤协作组(GETO)的治疗试验,使我们有望让50%的患者获得5年无病生存率,56%的患者获得5年总生存率。