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格陵兰岛膝关节原发性骨关节炎的流行病学

The epidemiology of primary osteoarthrosis of the knee in Greenland.

作者信息

Andersen S

出版信息

Scand J Rheumatol. 1978;7(2):109-12. doi: 10.3109/03009747809098846.

DOI:10.3109/03009747809098846
PMID:705266
Abstract

295 Greenlanders, 5% of the population of Greenland, in the age group 40 years or more, were investigated regarding primary oesteoarthrosis of the knee. The pathological changes were categorized as mid, intermediate, or severe. 86 (29%) of the subjects were found to have osteoarthrosis and the mild form accounted for 72% of these, while only one individual was found to have severe osteoarthrosis. Significantly more individuals from the West coast of Greenland (a mixed Eskimo-European population) as compared with individuals from the East coast (genuine Eskimos) were found to have osteoarthrosis of the knee (38% and 18%, respectively). An investigation of the sex distribution revealed more osteoarthrosis among West coast women than among East coast women (p is less than 0.05), whereas no such differences were found among the men. It was speculated that the difference between the prevalence rates of osteoarthrosis of the knee in the two population groups might reflect differences in occupation and possibly also a genetic predisposition.

摘要

对295名年龄在40岁及以上的格陵兰人(占格陵兰人口的5%)进行了膝关节原发性骨关节炎的调查。病理变化分为中度、中度和重度。86名(29%)受试者被发现患有骨关节炎,其中轻度形式占72%,而只有1人被发现患有重度骨关节炎。与东海岸(真正的爱斯基摩人)的个体相比,格陵兰西海岸(爱斯基摩 - 欧洲混血人群)有更多个体被发现患有膝关节骨关节炎(分别为38%和18%)。对性别分布的调查显示,西海岸女性的骨关节炎患者比东海岸女性更多(p小于0.05),而男性之间未发现此类差异。据推测,这两个人群组膝关节骨关节炎患病率的差异可能反映了职业差异,也可能反映了遗传易感性。

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