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自闭症儿童脑干功能障碍的临床关联

Clinical correlates of brainstem dysfunction in autistic children.

作者信息

Fein D, Skoff B, Mirsky A F

出版信息

J Autism Dev Disord. 1981 Sep;11(3):303-15. doi: 10.1007/BF01531513.

Abstract

Children with the diagnosis of autism were tested for brainstem auditory evoked potentials (BAEP), and information was gathered on their medical and developmental histories and current developmental levels of symptomatology. On comparing the nine autistic children having abnormal BAEPs and the seven autistic children with normal BAEPs, the former were found to have exhibited greater pathology in the areas of attention and social accessibility. No differences were found between the groups on measures of language, motor, or perceptual functioning, or on previous diagnoses or medical history. It is suggested that social attentional pathology may be more specifically associated with the brainstem pathology that may characterize autism than are symptoms in other developmental areas.

摘要

对被诊断为自闭症的儿童进行了脑干听觉诱发电位(BAEP)测试,并收集了他们的医疗和发育史以及当前症状的发育水平信息。在比较九名BAEP异常的自闭症儿童和七名BAEP正常的自闭症儿童时,发现前者在注意力和社交能力方面表现出更严重的病变。两组在语言、运动或感知功能测量方面,或在既往诊断或病史方面均未发现差异。研究表明,与其他发育领域的症状相比,社会注意力病变可能与自闭症所特有的脑干病变更具特异性关联。

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