García Villarrubia V, Moreno Koch M C
Rev Esp Oncol. 1981;28(2):169-94.
The authors consider three successive phenomena in the experimental Ca H tumor evolution. A first stage of tumor resistance due to cytotoxic cells in the presence of some suppressor cells; a second stage when suppressor activity is predominantly observed, and a final stage of lymphocyte-mediated immunostimulation. Vasodilatation and angiogenesis are probably important during third stage.
作者们考虑了实验性Ca H肿瘤演变过程中的三个连续现象。第一阶段是在存在一些抑制细胞的情况下，由于细胞毒性细胞导致的肿瘤抗性；第二阶段主要观察到抑制活性；以及淋巴细胞介导的免疫刺激的最后阶段。血管舒张和血管生成在第三阶段可能很重要。
