Tabár L, Dean P B
JAMA. 1982 Jan 8;247(2):185-9.
Mammographic parenchymal patterns, originally presented as a new risk factor for breast cancer, have been prospectively studied in a large (27,157 examinations) consecutive screening population. Although there is a significantly higher risk of breast cancer in the so-called dysplastic breasts (P2 and DY pattern groups), the classification is of little practical value, as more than 72% of the cancers in the prevalent population were found in the so-called low-risk breasts (N1 and P1 pattern groups). A similar trend occurred at repeated screening of younger women, in which most of the "incident" cancers were found in the "low-risk" breasts. These patterns should not be used to influence patient management or screening programs.
乳腺X线实质分型最初作为乳腺癌的一种新的风险因素被提出，已在一个大型（27157例检查）连续筛查人群中进行了前瞻性研究。尽管在所谓的发育异常乳房（P2和DY型组）中患乳腺癌的风险显著更高，但这种分类的实用价值不大，因为在现患人群中超过72%的癌症是在所谓的低风险乳房（N1和P1型组）中发现的。在对年轻女性的重复筛查中也出现了类似趋势，其中大多数“新发”癌症是在“低风险”乳房中发现的。这些分型不应被用于影响患者管理或筛查计划。
