大鼠脑中碘-125标记的三碘甲状腺原氨酸：在离散神经系统中定位的证据。
Iodine-125-labeled triiodothyronine in rat brain: evidence for localization in discrete neural systems.
作者信息
Dratman M B, Futaesaku Y, Crutchfield F L, Berman N, Payne B, Sar M, Stumpf W E
出版信息
Science. 1982 Jan 15;215(4530):309-12. doi: 10.1126/science.7053582.
PMID:7053582
Abstract
Autoradiograms prepared from adult rat brains demonstrate that nerve cells and neuropil in different brain regions selectively concentrate and retain intravenously administered triiodothyronine, by mechanisms susceptible to saturation with excess triiodothyronine. A neuroregulatory role for thyroid hormones, strongly supported by the observations, may account for their marked effects on behavior and the activity of the autonomic nervous system.
摘要
从成年大鼠大脑制备的放射自显影片表明，不同脑区的神经细胞和神经纤维通过易被过量三碘甲状腺原氨酸饱和的机制，选择性地浓缩并保留静脉注射的三碘甲状腺原氨酸。这些观察结果有力支持的甲状腺激素的神经调节作用，可能解释了它们对行为和自主神经系统活动的显著影响。
Zotero 插件