Walfish P G, Gryfe C I
Geriatrics. 1982 Jan;37(1):135-50.
Thyroid disease cannot be diagnosed through any single test. Normal aging does affect the values of some test parameters in the elderly. When interpreting laboratory test results in the elderly, careful consideration should be given to gender, concurrent acute or chronic illness, nutritional and mental status, as well as possible recent administration of iodinated radiocontrast media and drug therapy. When these factors have been excluded and preliminary routine thyroid function are abnormal or marginally suspect, the usual standards for younger adults, slightly modified, should suffice for diagnosing both hypo-and hyperthyroidism. Patients with complications may require special measurements of serum FT4 and FT3 levels as well as the TSH and T3 response to TRH. These tests will provide additional supportive diagnostic assistance.
甲状腺疾病无法通过任何单一检测来诊断。正常衰老确实会影响老年人某些检测参数的值。在解读老年人的实验室检测结果时,应仔细考虑性别、并发的急性或慢性疾病、营养和精神状态,以及近期是否可能使用过含碘放射性造影剂和药物治疗。当排除这些因素且初步常规甲状腺功能异常或略有可疑时,对年轻成年人的通常标准稍作修改,就足以诊断甲状腺功能减退和亢进。有并发症的患者可能需要特殊检测血清FT4和FT3水平以及TSH和T3对TRH的反应。这些检测将提供额外的支持性诊断帮助。