Critser E S, Savage P J, Rutledge J J, French L R
J Reprod Fertil. 1982 Jan;64(1):79-83. doi: 10.1530/jrf.0.0640079.
Hysterectomized pseudopregnant mice had plasma progesterone concentrations on Days 6, 8, 10 or 12 after mating that were greater (P less than 0.05) than those of intact pseudopregnant mice and lower (P less than 0.01) than those of pregnant mice. Concentrations of 13,14-dihydro-15-keto-prostaglandin F-2 alpha on Days 6, 7, 8, 9 or 10 after mating were lower (P less than 0.05) in pregnant and higher (P less than 0.01) in intact pseudopregnant mice than in hysterectomized pseudopregnant mice. The results support the conclusion that there are uterine and extra-uterine luteolytic mechanisms which are mediated by prostaglandin and are perhaps functional by Day 6 of pregnancy.
子宫切除的假孕小鼠在交配后第6、8、10或12天的血浆孕酮浓度高于完整假孕小鼠（P<0.05），但低于怀孕小鼠（P<0.01）。在交配后第6、7、8、9或10天，怀孕小鼠的13,14-二氢-15-酮-前列腺素F-2α浓度低于子宫切除的假孕小鼠（P<0.05），而完整假孕小鼠的该浓度则高于子宫切除的假孕小鼠（P<0.01）。这些结果支持以下结论：存在子宫和子宫外的黄体溶解机制，这些机制由前列腺素介导，可能在怀孕第6天起发挥作用。
