Koga S, Kaibara N, Kishimoto H, Nishidoi H, Kimura O, Okamoto T, Tamura H
Langenbecks Arch Chir. 1982;356(1):37-42. doi: 10.1007/BF01270600.
To evaluate whether it is appropriate to estimate the postoperative curability of gastric cancer based on the 5-year survival rate, we compared 5- and 10-year survival rates in 477 primary gastric cancer patients who had undergone gastrectomy during the 8-year period from 1960-1967. In patients who had died more than 5 years after surgery, the cause of death was investigated. The 10-year survival rate of 315 curatively operated patients was 59.1%, 2.9% lower than the 5-year survival rate. Of 176 patients who survived more than 5 years postoperatively, only 9 (5.1%) died of cancer recurrence, suggesting that the 5-year survival rate adequately reflects the curative success of gastric cancer surgery. The postoperative curability of gastric cancer is usually estimated by the 5-year survival rate. However, even in patients who survived for more than 5 years postoperatively, cancer recurrence has been observed. Therefore, we deemed it useful to assess whether it is appropriate to estimate the postoperative curability of gastric cancer based on the 5-year survival rate. From this point of view, we compared the 5- and 10-year survival rates of operated primary gastric patients and investigated the cause of death in patients who died more than 5 years postoperatively. Furthermore, in patients with cancer recurrence more than 5 years postoperatively, the pathologic findings on the cancer in the originally resected specimen were re-evaluated.
为评估基于5年生存率来估计胃癌术后治愈率是否合适，我们比较了1960年至1967年这8年间477例接受胃切除术的原发性胃癌患者的5年和10年生存率。对于术后死亡超过5年的患者，调查其死亡原因。315例接受根治性手术患者的10年生存率为59.1%，比5年生存率低2.9%。在术后存活超过5年的176例患者中，只有9例（5.1%）死于癌症复发，这表明5年生存率充分反映了胃癌手术的治愈成功情况。胃癌的术后治愈率通常通过5年生存率来估计。然而，即使在术后存活超过5年的患者中，也观察到了癌症复发。因此，我们认为评估基于5年生存率来估计胃癌术后治愈率是否合适是有用的。从这个角度出发，我们比较了接受手术的原发性胃癌患者的5年和10年生存率，并调查了术后死亡超过5年患者的死亡原因。此外，对于术后5年以上出现癌症复发的患者，对最初切除标本中的癌症病理结果进行了重新评估。
