Whitley N O, Brenner D E, Francis A, Villa Santa U, Aisner J, Wiernik P H, Whitley J
Radiology. 1982 Feb;142(2):439-46. doi: 10.1148/radiology.142.2.7054834.
To assess the accuracy of computed tomography (CT) in staging advanced carcinoma of the cervix, 18 staging evaluations were performed in 16 patients with locally advanced (FIGO Stage IB-IVA) cervical carcinoma. CT staging results were compared with the results of clinical staging and postoperative staging. CT was accurate in 12/18 (66%) cases, clinical staging was accurate in 10/18 (55%) cases, and clinical staging with cystoscopy was accurate in 14/18 (78%) cases. CT staging failed to detect microscopic pelvic sidewall involvement and bladder involvement when there was no contrast material in the bladder. In the detection of para-aortic lymph node involvement by tumor, there were 12 true-negative, 4 true-positive, 1 false-positive, and 1 false-negative study (sensitivity = 80%, specificity = 92%). It is concluded that CT is equal in accuracy to other clinical staging techniques and offers the advantage of visualizing the tumor, which allows for more accurate determination of radiation portals.
为评估计算机断层扫描（CT）在晚期宫颈癌分期中的准确性，对16例局部晚期（国际妇产科联盟[FIGO]分期为IB-IVA期）宫颈癌患者进行了18次分期评估。将CT分期结果与临床分期及术后分期结果进行比较。CT在12/18（66%）的病例中分期准确，临床分期在10/18（55%）的病例中准确，临床分期联合膀胱镜检查在14/18（78%）的病例中准确。当膀胱内无对比剂时，CT分期未能检测到显微镜下的盆腔侧壁受累及膀胱受累情况。在检测肿瘤对主动脉旁淋巴结的累及方面，有12次真阴性、4次真阳性、1次假阳性和1次假阴性研究（敏感性 = 80%，特异性 = 92%）。结论是，CT在准确性上与其他临床分期技术相当，且具有可视化肿瘤的优势，这有助于更准确地确定放疗野。
