Husni E A, Williams W A
Surgery. 1982 Jan;91(1):70-4.
In the absence of malignancy, thrombophlebitis of the lower limb is invariably associated with pre-existent varicose veins. Not until pulmonary embolism was reported to occur in superficial phlebitis did the clinician introduce anticoagulants and/or surgery in the management of this condition. In an effort to reach an effective approach to this problem, 1,000 consecutive cases of varicose veins of the lower limbs were reviewed. Of these patients, 779 were admitted for elective vein ligation and stripping and 221 presented with thrombophlebitis. The latter group was subdivided into four categories according to the mode of management: (1) local heat and anti-inflammatory agents, 60 cases; (2) anticoagulants, 22 cases; (3) phlebotomy, high saphenous ligation and anticoagulation, 4 cases; and (4) ligation and stripping, 135 cases. In category 4 the saphenous is removed in a routine fashion together wih all its tributaries. All perforators are exposed, evacuated of thrombus when present, and ligated subfascially. Thrombi were encountered in one or more perforating veins in 10 patients, but no pulmonary embolism was observed in this group of patients. All instances of documented pulmonary embolism (10 cases) occurred in category 1 with one fatality. The incidence of pulmonary embolism in the elective group of ligation and stripping (without phlebitis) was 0.5%. The data indicate that the surgical approach is safe and preferable to the other modalities for several reasons: (1) It eliminates the varicosities and the phlebitic process simultaneously, (2) a single hospitalization is necessary (cost effectiveness), and (3) no anticoagulants are needed. If, for any reason, surgery cannot be undertaken, then anticoagulants should be employed in an effort to avoid thromboembolism.
在没有恶性肿瘤的情况下,下肢血栓性静脉炎总是与先前存在的静脉曲张相关。直到有报道称浅静脉炎会发生肺栓塞后,临床医生才在这种疾病的治疗中引入抗凝剂和/或手术。为了找到解决这个问题的有效方法,对1000例连续的下肢静脉曲张病例进行了回顾。在这些患者中,779例因择期静脉结扎和剥脱术入院,221例出现血栓性静脉炎。后一组根据治疗方式分为四类:(1)局部热敷和抗炎药,60例;(2)抗凝剂,22例;(3)放血、大隐静脉高位结扎和抗凝,4例;(4)结扎和剥脱术,135例。在第4类中,大隐静脉及其所有属支以常规方式切除。所有穿通静脉均暴露,如有血栓则清除,并在筋膜下结扎。10例患者的一条或多条穿通静脉中发现血栓,但该组患者未观察到肺栓塞。所有记录在案的肺栓塞病例(10例)均发生在第1类,其中1例死亡。择期结扎和剥脱术组(无静脉炎)的肺栓塞发生率为0.5%。数据表明,手术方法是安全的,并且由于以下几个原因优于其他治疗方式:(1)它能同时消除静脉曲张和静脉炎过程;(2)只需住院一次(成本效益高);(3)不需要抗凝剂。如果由于任何原因无法进行手术,那么应使用抗凝剂以避免血栓栓塞。