le Roux F B, van Buuren A J
S Afr Med J. 1978 Jul 29;54(5):205-8.
A 21-month old infant with endemic syphilis who presented with nephrotic syndrome is described. Clinically, the features correlated well with those of renal disease associated with secondary syphilis. The onset of renal disease in association with syphilis after early infancy may be a valuable aid in drawing attention to the possibility of endemic syphilis. Morphologically the features were those of an immune complex-mediated glomerulonephritis. We regard the presence of a large number of immature-looking glomeruli as a retrogressive phenomenon.
本文描述了一名患有地方性梅毒且表现为肾病综合征的21个月大婴儿。临床上,其特征与二期梅毒相关肾病的特征高度相符。婴儿早期之后出现与梅毒相关的肾病,可能有助于引起人们对地方性梅毒可能性的关注。形态学上,其特征为免疫复合物介导的肾小球肾炎。我们认为大量看起来不成熟的肾小球的存在是一种退行性现象。