Oliveros R, Vallo A, Bilbao F, Fidalgo I, Rodríguez Soriano J
An Esp Pediatr. 1976 Sep-Oct;9(5):532-7.
Clinical and renal morphologic studies are reported in a 3 1/2 month old infant with congenital syphilis and nephrotic syndrome. Renal lesions were consistent with membranous proliferative glomerulonephritis, and the presence of glomerular deposits of IgM, C3, and of less intensity of IgE and fibrin, were demonstrated by means of immunofluorescence. These findings identify the renal lesion as an immune glomerulopathy. A therapeutic course of penicillin resulted in resolution of clinical manifestations without any evidence of persistent renal damage.
报告了一名患有先天性梅毒和肾病综合征的3个半月大婴儿的临床和肾脏形态学研究。肾脏病变符合膜增生性肾小球肾炎，通过免疫荧光法证实存在IgM、C3的肾小球沉积物，以及强度较低的IgE和纤维蛋白沉积物。这些发现确定肾脏病变为免疫性肾小球病。青霉素治疗疗程使临床表现消退，没有任何持续性肾脏损伤的证据。
