Allum J H, Hepp-Reymond M C, Gysin R
Brain Res. 1982 Jan 14;231(2):325-34. doi: 10.1016/0006-8993(82)90369-9.
Pairs of neurones were recorded within the hand region of the precentral motor cortex of monkeys trained to squeeze a force transducer between the thumb and index finger. Neuronal discharges of a pair of cells, recorded through the same electrode, were first examined for their co-variation with force. The discharges of those pairs with a consistent co-variation were cross-correlated during periods of constant isometric force. Cross-correlograms in the majority of cases had either a sharp peak or trough at latencies suggesting monosynaptic causal relations between the cell discharges. A peak was associated with pairs of cells whose discharges co-varied similarly with force and when a trough was observed, the cell discharges of the pair generally differed in their force co-variation. It is concluded that the action of motor cortical neurones is linked by common and recurrent collateral inputs during isometric co-contraction of finger muscles.
在经过训练用拇指和食指挤压力传感器的猴子的中央前运动皮层手部区域内，记录成对的神经元。通过同一电极记录的一对细胞的神经元放电，首先检查它们与力的共变情况。在等长力恒定的时间段内，对那些具有一致共变的成对放电进行互相关分析。在大多数情况下，互相关图在潜伏期有尖锐的峰值或谷值，这表明细胞放电之间存在单突触因果关系。峰值与放电随力有相似共变的细胞对相关，当观察到谷值时，该对细胞的放电在力的共变方面通常不同。得出的结论是，在手指肌肉等长协同收缩过程中，运动皮层神经元的活动通过共同的和反复的侧支输入相联系。
