来自甲基化透明质酸的2-乙酰氨基-2-脱氧-3-O-（β-D-吡喃葡萄糖醛酸）-D-葡萄糖（透明双糖醛酸）的甲基衍生物
Methyl derivatives of 2-acetamido-2-deoxy-3-O-(beta-D-glucopyranosyluronic acid)-D-glucose (hyalobiouronic acid) from methylated hyaluronic acid.
作者信息
Jeanloz R W
出版信息
Carbohydr Res. 1982 Jan 1;99(1):51-8. doi: 10.1016/s0008-6215(00)80974-x.
PMID:7055825
Abstract
Methanolysis of methylated hyaluronic acid, followed by acetylation, gave, in 70% yield, crystalline methyl 2-acetamido-2-deoxy-4,6-di-O-methyl-3-O-(methyl 4-O-acetyl-2,3-di-O-methyl-beta-D-glucopyranosyluronate) -alpha-D-glucopyranoside. Removal of the O-acetyl and methyl ester groups gave compounds that are useful in the investigation, by 1H-n.m.r. spectroscopy, of interaction within chains of hyaluronic acid in solution.
摘要
甲基化透明质酸经甲醇解，再进行乙酰化反应，以70%的产率得到结晶状的甲基2-乙酰氨基-2-脱氧-4,6-二-O-甲基-3-O-(甲基4-O-乙酰基-2,3-二-O-甲基-β-D-吡喃葡萄糖醛酸苷)-α-D-吡喃葡萄糖苷。去除O-乙酰基和甲酯基团后得到的化合物，可用于通过¹H-核磁共振光谱研究溶液中透明质酸链内的相互作用。
Zotero 插件