Rudy Y, Wood R, Plonsey R, Liebman J
Circulation. 1982 Mar;65(3):440-5. doi: 10.1161/01.cir.65.3.440.
The effect of increased lung conductivity on ECG potentials was studied in human subjects undergoing pulmonary lavage of a whole lung. In this procedure, the air in the lung is replaced by physiologic saline solution, which is a highly conductive fluid. The same situation was simulated theoretically with an eccentric spherical model of the heart and torso. Both the experimental results and theoretical simulations show a decrease in body-surface potentials as the lung conductivity increases. In particular, a large decrease was observed in the posterior vector and the scalar Z lead both experimentally and theoretically. The model simulation shows that the scalar Z lead is maximal at a conductivity value that is very close to the typical normal lung conductivity, so that low voltages are predicted for low lung conductivities as well.
在接受全肺灌洗的人体受试者中，研究了肺传导性增加对心电图电位的影响。在这个过程中，肺内的空气被生理盐溶液取代，生理盐溶液是一种高传导性液体。用心脏和躯干的偏心球模型从理论上模拟了相同的情况。实验结果和理论模拟均表明，随着肺传导性的增加，体表电位降低。特别是，在实验和理论上均观察到后向向量和标量Z导联有大幅下降。模型模拟表明，标量Z导联在一个非常接近典型正常肺传导性的传导率值时达到最大值，因此对于低肺传导率也预测会出现低电压。
