Tabatabai M
Experientia. 1982 Jan 15;38(1):107. doi: 10.1007/BF01944555.
Intramuscular injection of 17 beta-estradiol to pregnant rabbits did not produce any significant change in the phospholipid, neutral lipid and cholesterol content of the fetal brains, nor did it cause any significant difference in their wet and dry weights. It may be inferred that use of estrogen in the gestational period to enhance surfactant production and lung maturation in the fetus would not produce adverse effects on the fetal brain lipids.
给怀孕兔子肌肉注射17β-雌二醇，并未使胎脑的磷脂、中性脂质和胆固醇含量发生任何显著变化，也未使其湿重和干重出现任何显著差异。可以推断，孕期使用雌激素来提高胎儿表面活性物质的产生和肺成熟度，不会对胎儿脑脂质产生不利影响。
