Thomsen R J, Zuehlke R L, Beckman B I
J Dermatol Surg Oncol. 1982 Jan;8(1):24-8. doi: 10.1111/j.1524-4725.1982.tb00229.x.
The fingernails of a woman with pachyonychia congenita were ablated by several different methods. The most effective, most rapidly performed, and most acceptable method was vigorous curettage and electrofulguration of the matrices and beds of the nails. The responses to treatment suggest that the matrix, rather than the bed, is the site from which the abnormality of the nails develops in pachyonychia congenita. Removal of the nail beds is not necessary to prevent recurrence of deformed nails, but it may reduce hyperkeratosis in their sites.
一位先天性厚甲症女性的指甲通过几种不同方法被切除。最有效、操作最迅速且最易接受的方法是对甲母质和甲床进行大力刮除和电灼。治疗反应表明，在先天性厚甲症中，指甲异常是从甲母质而非甲床发展而来。为防止指甲变形复发，无需切除甲床，但这可能会减轻其部位的角化过度。
