大鼠血小板中的磷酸肌酸
Creatine phosphate in rat blood platelets.
作者信息
Shibata S
出版信息
Thromb Haemost. 1978 Jun 30;39(3):707-11.
PMID:705699
Abstract
Creatine phosphate (CP) was found in rat platelets by an assay method devised to increase the specificity and sensitivity. In this method, radioactivity of [14C]ATP was measured after the reaction of CP with [14C]ADP in the presence of creatine kinase. The mean value of the CP content in rat platelets was 24.8 nmoles per 10(9) platelets. Since the molar ratio of CP and ATP was 1:2.6, it is probable that CP plays a role in the energy metabolism of rat platelets.
摘要
通过一种旨在提高特异性和灵敏度而设计的测定方法，在大鼠血小板中发现了磷酸肌酸（CP）。在该方法中，在肌酸激酶存在的情况下，CP与[14C]ADP反应后，测量[14C]ATP的放射性。大鼠血小板中CP含量的平均值为每10（9）个血小板24.8纳摩尔。由于CP与ATP的摩尔比为1:2.6，因此CP很可能在大鼠血小板的能量代谢中发挥作用。
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