Vande Berg J S, Devine C J, Horton C E, Somers K D, Wright G L, Leffell M S, Dawson D M, Gleischman S H, Rowe M J
J Urol. 1982 Jan;127(1):52-4. doi: 10.1016/s0022-5347(17)53599-5.
Scanning and transmission electron micrographs demonstrate a calcification process in the penile plaques of patients with Peyronie's disease. Osteoid formation originates from vascular lumina via osteoblast-like cells, which align the calcified plaque. These cells are surrounded gradually by calcified connective tissue. Collagen fibers demonstrate calcification and decreased periodicity.