Pearson C M, Edwards K
Mutat Res. 1982 Jan-Feb;100(1-4):211-4. doi: 10.1016/0165-1218(82)90046-5.
The ability of 4CMB to induce repair phenomena has been investigated in 3 types of assay. No significant unscheduled DNA synthesis or repair replication was found, although the compound gave a weakly positive dose-related response in strand-break assays, with 250 microgram/ml producing significant amounts of strand breaks. These data indicate that 4CMB is a weakly genotoxic agent.
已通过3种检测方法研究了4CMB诱导修复现象的能力。尽管该化合物在链断裂检测中呈现出微弱的剂量相关阳性反应，250微克/毫升时会产生大量链断裂，但未发现明显的非预定DNA合成或修复复制现象。这些数据表明4CMB是一种弱基因毒性剂。
