4-氯甲基联苯（4CMB）、苄基氯（BC）和4-羟甲基联苯（4HMB）：利用鼠伤寒沙门氏菌对其致突变潜力的评估
4-Chloromethylbiphenyl (4CMB), benzyl chloride (BC) and 4-hydroxymethylbiphenyl (4HMB): an evaluation of their mutagenic potential using Salmonella typhimurium.
作者信息
Jones E, Richold M
出版信息
Mutat Res. 1982 Jan-Feb;100(1-4):49-54. doi: 10.1016/0165-1218(82)90020-9.
PMID:7035900
Abstract
The 3 compounds 4CMB, BC and 4HMB were tested using the "Ames' Salmonella assay. 4CMB produced a strong mutagenic response; no evidence of mutagenic activity was obtained with BC and 4HMB. Urine from mice treated with the 3 compounds was also tested. None of the urine samples produced a mutagenic response.
摘要
使用“Ames沙门氏菌试验”对4 - 氯 - 邻甲苯胺（4CMB）、苄基氯（BC）和4 - 羟基 - 邻甲苯胺（4HMB）这3种化合物进行了测试。4CMB产生了强烈的诱变反应；而BC和4HMB未获得诱变活性的证据。还用这3种化合物处理过的小鼠尿液进行了测试。所有尿液样本均未产生诱变反应。
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