4CMB对小鼠生殖细胞的影响。
The effect of 4CMB on germ cells of the mouse.
作者信息
Brook J D
出版信息
Mutat Res. 1982 Jan-Feb;100(1-4):305-8. doi: 10.1016/0165-1218(82)90066-0.
PMID:7057766
Abstract
The effect of 4CMB on meiosis in the mouse was studied using both male and female test systems. Females were superovulated and treated with 4CMB at metaphase I and oocytes sampled at metaphase II. Similarly with males, chromosome analysis was made at metaphase II for spermatocytes treated at metaphase I. No increase in the frequency of structural of numerical chromosome abnormalities was noted for treated mice as compared to controls.
摘要
使用雄性和雌性测试系统研究了4CMB对小鼠减数分裂的影响。对雌性小鼠进行超排卵处理，并在减数分裂中期I用4CMB处理，然后在减数分裂中期II采集卵母细胞。雄性小鼠的处理方式类似，在减数分裂中期I用4CMB处理精母细胞，并在减数分裂中期II进行染色体分析。与对照组相比，未观察到处理组小鼠染色体结构或数目异常频率增加。
相似文献
1
The effect of 4CMB on germ cells of the mouse.4CMB对小鼠生殖细胞的影响。
Mutat Res. 1982 Jan-Feb;100(1-4):305-8. doi: 10.1016/0165-1218(82)90066-0.
2
UKEMS collaborative genotoxicity trial. Cytogenetic tests of 4CMB, BC and 4HMB: summary and appraisal.
Mutat Res. 1982 Jan-Feb;100(1-4):313-31. doi: 10.1016/0165-1218(82)90068-4.
3
Effects of hyperstimulation with gonadotrophins and age of females on oocytes and their metaphase II status in rats.促性腺激素超刺激及雌性大鼠年龄对卵母细胞及其减数分裂中期II状态的影响。
Mol Reprod Dev. 2000 Jan;55(1):104-8. doi: 10.1002/(SICI)1098-2795(200001)55:1<104::AID-MRD14>3.0.CO;2-J.
4
Metaphase analysis of human lymphocytes treated with 4-chloromethylbiphenyl and benzyl chloride.用4-氯甲基联苯和苄基氯处理的人淋巴细胞的中期分析。
Mutat Res. 1982 Jan-Feb;100(1-4):297-9. doi: 10.1016/0165-1218(82)90064-7.
5
[The effect of different doses of gonadotropins on the quantitative, morphological and cytogenetic characteristics of oocytes from CBA mice].
Tsitol Genet. 1999 Jan-Feb;33(1):49-53.
6
Meiosis suppression by caffeine in female mice.咖啡因对雌性小鼠减数分裂的抑制作用。
Mol Gen Genet. 1972;118(3):209-14. doi: 10.1007/BF00333457.
7
Mechanism of chromosome aberration induction in the mouse egg fertilized with sperm recovered from postmeiotic germ cells treated with methyl methanesulfonate.用甲磺酸甲酯处理减数分裂后生殖细胞所获精子使小鼠卵子受精后诱导染色体畸变的机制。
Mutat Res. 1989 Oct;214(2):165-80. doi: 10.1016/0027-5107(89)90161-9.
8
The effects of BC, 4CMB and 4HMB on meiosis in yeast cells.
Mutat Res. 1982 Jan-Feb;100(1-4):173-7. doi: 10.1016/0165-1218(82)90041-6.
9
4-Chloromethylbiphenyl (4CMB)--an in vivo cytogenetic study in the Chinese hamster (Cricetulus griseus).4-氯甲基联苯（4CMB）——中国仓鼠（黑线仓鼠）体内细胞遗传学研究
Mutat Res. 1982 Jan-Feb;100(1-4):309-12. doi: 10.1016/0165-1218(82)90067-2.
10
Response of mouse ovaries in vivo and in organ culture to pregnant mare's serum gonadotrophin and human chorionic gonadotrophin.小鼠卵巢在体内及器官培养中对孕马血清促性腺激素和人绒毛膜促性腺激素的反应。
J Reprod Fertil. 1973 Jun;33(3):399-401. doi: 10.1530/jrf.0.0330399.
Zotero 插件