Gore S, Langlands A, Pocock S, Kerr G
Recent Results Cancer Res. 1982;80:134-41. doi: 10.1007/978-3-642-81685-7_23.
Retrospective analysis was made of 3,918 cases of breast cancer seen during 1954-1964. Median survival was 4.5 years and 30% of patients survived through a 10-year period. For stages I, II, and III patients, the mortality increased during 1-4 years after diagnosis and then slowly declined. Beyond 15 years, stage III patients assumed the same mortality (5%) as those with lesser disease; 58% excess of deaths from all causes after 15-20 years showed that breast cancer was not curable within 20 years but ultimately, taking account of clinical status, 51% of 5-year survivors with stages I-III disease are cured.
对1954年至1964年间收治的3918例乳腺癌患者进行了回顾性分析。中位生存期为4.5年,30%的患者存活了10年。对于I期、II期和III期患者,诊断后1至4年死亡率上升,然后缓慢下降。15年后,III期患者的死亡率与病情较轻的患者相同(5%);15至20年后,所有原因导致的死亡人数多出58%,这表明乳腺癌在20年内无法治愈,但最终,考虑到临床状况,I至III期疾病的5年存活者中有51%被治愈。