Ruiter A
Tijdschr Diergeneeskd. 1982 Feb 1;107(3):85-92.
Products of animal origin may contain a variety of substances regarded as 'residues': traces of veterinary drugs and their metabolites, environmental contaminants, traces of compounds having injurious effects, which have their origin in the manufacturing process, and mycotoxins. Some of these substances are carcinogenic, others may impair the functions of organs or cause disturbances of hormonal balance. Antibacterial substances may induce resistance of pathogenic agents and, finally, a number of substances give rise to sensitivity reactions. Standards for permissible amounts are required in several cases; a number of substances should be completely omitted so that their use should be prohibited; adopting the concept of 'zero tolerance', however, may present problems. Extensive analysis is only practicable so far in a few cases. Rapid screening procedures will have to be developed in the future, in which immunochemical methods may play a particularly important role.
动物源性产品可能含有多种被视为“残留物”的物质：兽药及其代谢物的痕迹、环境污染物、源自生产过程的具有有害影响的化合物痕迹以及霉菌毒素。其中一些物质具有致癌性，其他物质可能损害器官功能或导致激素平衡紊乱。抗菌物质可能会诱导病原体产生耐药性，最后，一些物质会引发过敏反应。在某些情况下需要制定允许含量标准；一些物质应完全剔除，即应禁止使用；然而，采用“零容忍”概念可能会带来问题。到目前为止，广泛的分析仅在少数情况下可行。未来必须开发快速筛查程序，免疫化学方法在其中可能会发挥特别重要的作用。
