Karanova M V, Budantsev A Iu, Brazhnik E S
Ukr Biokhim Zh (1978). 1982;54(1):82-5.
Electrophoresis separation of membrane acetylcholinesterase in 5% PAAG resulted in five forms of the enzyme differing by electrophoretic mobility and velocity of ACh hydrolysis. The activity of isoforms (I, II) was decreased by 40 and 76, respectively, 4 days after deafferentiation of septo-hippocampal pathways. Changes in the activity were still greater 7 days after deafferentiation as compared with those mentioned above.
在5%聚丙烯酰胺凝胶中对膜乙酰胆碱酯酶进行电泳分离,得到了该酶的五种形式,它们在电泳迁移率和乙酰胆碱水解速度上存在差异。在海马隔区通路去传入神经4天后,同工型(I、II)的活性分别降低了40%和76%。去传入神经7天后,与上述情况相比,活性变化更大。