Crawford E D, Skinner D G
Urology. 1982 Jan;19(1):25-8. doi: 10.1016/0090-4295(82)90039-5.
A double-blind study was done in 90 patients undergoing a rib-resecting thoracoabdominal incision for testicular cancer or a flank incision for renal surgery to determine the effect of intraoperative intercostal nerve block with bupivacaine hydrochloride on postoperative pain and complications, day of ambulation, and day of oral fluid intake. In the patients treated with bupivacaine, we found a significant reduction in the amount of postoperative analgesia required, but no difference in the day of ambulation or fluid intake. Ten of 45 patients given a placebo nerve block experienced postoperative atelectasis, whereas only 4 of 45 patients in the treated group experienced this complication. We believe that intercostal nerve block is a valuable postoperative adjuvant in patients undergoing flank surgery to reduce the postoperative analgesic requirements and incidence of atelectasis.
对90例接受肋骨切除胸腹切口睾丸癌手术或经腰切口肾脏手术的患者进行了一项双盲研究，以确定术中用盐酸布比卡因进行肋间神经阻滞对术后疼痛和并发症、下床活动日期及开始经口进食日期的影响。在用布比卡因治疗的患者中，我们发现术后所需镇痛药量显著减少，但下床活动日期或经口进食日期并无差异。接受安慰剂神经阻滞的45例患者中有10例发生术后肺不张，而治疗组45例患者中只有4例发生该并发症。我们认为肋间神经阻滞对于接受侧腹手术的患者是一种有价值的术后辅助治疗方法，可减少术后镇痛需求及肺不张的发生率。
