Tomasello F, Albanese V, Picozzi P, Spadaro A, Conforti P
Acta Neurochir (Wien). 1982;60(1-2):55-62. doi: 10.1007/BF01401750.
An investigation was carried out in 28 patients in order to evaluate the relationship between angiographically documented vasospasm, amount of subarachnoid blood found at surgery around ruptured intracranial aneurysms, and delayed ischaemic deficits. Angiography was performed at time intervals ranging between 5 and 17 days, and surgery not later than 21 days following subarachnoid haemorrhage. The absence of subarachnoid clots was associated in ten patients, with no or minor vasospasm and no or mild neurological deficits. Thin clots were found in eight patients; one of them had no vasospasm, six had minor vasospasm, and one showed severe vessel narrowing. Major clinical signs were absent in these cases. All ten patients with thick clots developed severe vasospasm, and eight of them severe neurological signs. The important aetiological role of local subarachnoid clots developed severe vasospasm, and eight of them severe neurological signs. The important aetiological role of local subarachnoid clots in determining vasospasm in emphasized in view of surgical timing.
对28例患者进行了一项调查,以评估血管造影记录的血管痉挛、颅内动脉瘤破裂时手术中发现的蛛网膜下腔出血量与延迟性缺血性神经功能缺损之间的关系。血管造影在蛛网膜下腔出血后5至17天内进行,手术不迟于21天。10例患者蛛网膜下腔无血凝块,无或仅有轻微血管痉挛,无或仅有轻度神经功能缺损。8例患者发现有薄血凝块;其中1例无血管痉挛,6例有轻微血管痉挛,1例显示严重血管狭窄。这些病例均无主要临床体征。所有10例有厚血凝块的患者均发生严重血管痉挛,其中8例出现严重神经体征。局部蛛网膜下腔血凝块在决定血管痉挛方面的重要病因学作用,鉴于手术时机而得到强调。