Millikan C H
Arch Neurol. 1975 Jul;32(7):433-49. doi: 10.1001/archneur.1975.00490490037003.
The literature concerning cerebral vasospasm associated with subarachnoid hemorrhage (SAH) due to ruptured intracranial aneurysm contains no definitive study of patients to determine whether there is (1) any clinical picture consistently present coincident with known cerebral vasospasm, (2) any relationship between mortality and known vasospasm, and (3) any relationship between serious brain damage (morbidity) and known vasospasm. To answer these important questions, experience with 198 consecutive acute SAH patients (every patient had a cerebral angiogram demonstrating one or more intracranial aneurysms) was studied. The experience with these 198 consecutive patients led to the conclusions that (1) there is no clinical picture consistently present coincident with known cerebral vasospasm; (2) cerebral vasospasm has no effect on the mortality from SAH due to ruptured aneurysm; and (3) there is no relationship between the frequency and severity of the complications from surgical or conservative treatment and the presence or absence of vasospasm.
关于颅内动脉瘤破裂导致蛛网膜下腔出血(SAH)相关的脑血管痉挛的文献中,没有对患者进行的确定性研究来确定是否存在:(1)与已知脑血管痉挛同时出现的任何一致的临床症状;(2)死亡率与已知脑血管痉挛之间的任何关系;(3)严重脑损伤(发病率)与已知脑血管痉挛之间的任何关系。为了回答这些重要问题,对198例连续急性SAH患者(每位患者均有脑血管造影显示一个或多个颅内动脉瘤)的经验进行了研究。对这198例连续患者的经验得出以下结论:(1)没有与已知脑血管痉挛同时出现的一致临床症状;(2)脑血管痉挛对破裂动脉瘤引起的SAH死亡率没有影响;(3)手术或保守治疗并发症的频率和严重程度与是否存在脑血管痉挛之间没有关系。