Butenko G M, Ivanova N I
Tsitol Genet. 1978 Jul-Aug;12(4):295-8.
A study of the phagocytic activity in young and old rats showed that the amount of functionally active cells among macrophages of the peritoneal exudate falls with ageing. The ability of macrophages to fix, absorb and digest heterologous cells (chicken erythrocytes) decreases. This decrease of phagocytic activity is to a considerable extent due to serum factors. Probably, the age changes in the macrophages functional activity play a definite role in decreasing the efficiency of defence mechanisms during senescence.
一项针对年轻和老年大鼠吞噬活性的研究表明，随着年龄增长，腹腔渗出液巨噬细胞中功能活跃细胞的数量会下降。巨噬细胞固定、摄取和消化异源细胞（鸡红细胞）的能力降低。吞噬活性的这种下降在很大程度上归因于血清因子。巨噬细胞功能活性的年龄变化可能在衰老过程中防御机制效率降低方面起到一定作用。
