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稳态高压暴露期间的氮消除

Nitrogen elimination during steady-state hyperbaric exposures.

作者信息

Vorosmarti J, Barnard E E, Williams J, de G Hanson R

出版信息

Undersea Biomed Res. 1978 Sep;5(3):243-52.

PMID:705941
Abstract

Nitrogen elimination was measured in six divers during steady-state exposures in an oxygen-nitrogen atmosphere at 1, 2, and 3 ATA using both oxy-helium and pure O2 as washout gases. This was accomplished by using mass spectrometry to measure the expired N2 concentration breath-by-breath over periods of 120 min in all experimental conditions except for O2 breathing at 3 ATA, which was limited to 30-min periods. In all cases the area under the elimination curve increased with pressure. Total area under the curve was also greater when breathing O2 than when breathing oxy-helium, but this difference decreased with depth and washout time. Nitrogen elimination on a semilogarithmic plot falls rapidly during the first four minutes and then shows a slow linear fall for the remainder of the measurement period. Effective elimination of nitrogen decreased with depth and oxygen was more effective than oxy-helium in washing out nitrogen at all depths studied. Possible causes of the different variations noted in the washout curves during the experiment are discussed.

摘要

在1、2和3个绝对大气压(ATA)的氧氮环境中,对6名潜水员进行稳态暴露时,使用氧氦混合气和纯氧作为冲洗气体来测量氮的排出量。这是通过质谱法在除3 ATA下呼吸纯氧(该情况限于30分钟时间段)之外的所有实验条件下,逐次呼吸测量120分钟时间段内呼出的氮气浓度来实现的。在所有情况下,排出曲线下的面积随压力增加。呼吸纯氧时曲线下的总面积也比呼吸氧氦混合气时更大,但这种差异随深度和冲洗时间而减小。在半对数图上,氮的排出在最初四分钟内迅速下降,然后在测量期的剩余时间内呈缓慢线性下降。有效氮排出量随深度降低,并且在所有研究深度下,氧气在冲洗氮气方面比氧氦混合气更有效。文中讨论了实验期间冲洗曲线中观察到的不同变化的可能原因。

相似文献

1
Nitrogen elimination during steady-state hyperbaric exposures.稳态高压暴露期间的氮消除
Undersea Biomed Res. 1978 Sep;5(3):243-52.
2
Nitrogen elimination in man during decompression.减压过程中人体的氮排出
Undersea Biomed Res. 1975 Dec;2(4):285-97.
3
Longitudinal study of performance after deep compressions with heliox and He-N2-O2.
Undersea Biomed Res. 1976 Sep;3(3):205-16.
4
Optimal use of nitrogen to suppress the high pressure nervous syndrome.优化氮的使用以抑制高压神经综合征。
Aviat Space Environ Med. 1975 Jan;46(1):37-40.
5
Decompression comparison of N2 and O2 in rats.大鼠体内氮气和氧气的减压比较
Undersea Biomed Res. 1991 Jul;18(4):317-31.
6
Decompression induced nitrogen elimination.减压诱导的氮气排出。
Undersea Biomed Res. 1984 Dec;11(4):369-80.
7
Measurement of helium elimination from man during decompression breathing air or oxygen.在减压呼吸空气或氧气过程中对人体氦气排出量的测量。
Undersea Biomed Res. 1975 Dec;2(4):277-84.
8
Gender differences in human skeletal muscle and subcutaneous tissue gases under ambient and hyperbaric oxygen conditions.环境和高压氧条件下人体骨骼肌和皮下组织气体的性别差异。
Undersea Hyperb Med. 2007 May-Jun;34(3):147-61.
9
Is the rate of whole-body nitrogen elimination influenced by exercise?全身氮排出率受运动影响吗?
Undersea Hyperb Med. 2012 Jan-Feb;39(1):595-604.
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On half-clearance time of carbon monoxide hemoglobin in blood during hyperbaric oxygen therapy (OHP).高压氧治疗期间血液中碳氧血红蛋白的半清除时间。
Bull Tokyo Med Dent Univ. 1975 Mar;22(1):63-77.

引用本文的文献

1
The physiological kinetics of nitrogen and the prevention of decompression sickness.氮的生理动力学与减压病的预防
Clin Pharmacokinet. 2001 Jan;40(1):1-14. doi: 10.2165/00003088-200140010-00001.