van Gool J D, Schmidt R A, Tanagho E A
Urol Int. 1978;33(5):293-303. doi: 10.1159/000280214.
Reflexes concerned with viscerosomatic and somatovisceral interplay in the sacral spinal cord were evaluated in spinalized animals, as part of a study on direct spinal cord stimulation of micturition. Urodynamic evaluation consisted of continuous recording of bladder pressure, urethral pressures and electromyograms of striated anal and urethral sphincters. All exteroceptive stimuli to urethral or anal mucosa caused an inappropriate increase in afferent input to the sacral micturition center: such stimuli should be avoided in the evaluation of suprasacral lesions of bladder innervation. Early in the spinal shock phase, hyperreflexia of striated pelvic floor muscles was apparent, in the absence of detrusor reflex activity. Clinical implications for early management of neurogenic bladder dysfunction are discussed. In all spinalized animals early balanced bladder function could be achieved, due to the absence of detrusor-sphincter dyssynergia: the opposite is true for spinalized man.
作为对脊髓直接刺激排尿研究的一部分，在脊髓损伤动物中评估了与骶段脊髓内脏-躯体和躯体-内脏相互作用有关的反射。尿动力学评估包括连续记录膀胱压力、尿道压力以及肛门和尿道横纹肌括约肌的肌电图。对尿道或肛门黏膜的所有外感受性刺激都会导致传入骶段排尿中枢的输入不适当增加：在评估膀胱神经支配的骶上病变时应避免此类刺激。在脊髓休克期早期，在无逼尿肌反射活动的情况下，盆底横纹肌的反射亢进很明显。讨论了对神经源性膀胱功能障碍早期管理的临床意义。由于不存在逼尿肌-括约肌协同失调，在所有脊髓损伤动物中均可早期实现膀胱功能平衡：而脊髓损伤的人则相反。
